14-3-3 PROTEIN, CSF (PRION DISEASE)

Specimen Required
Collect CSF - do not send the first 2.0 mL of CSF flow from tap. Send 5.0 mL CSF (2.0 mL minimum) frozen within 20 minutes of collection, in a screw-capped plastic vial. A random urine is requested, but not required. A patient information form completed by the referring health care professional is required. Please call client service for a form. The ordering physician name and phone number are required by the National Prion Lab. If patient resides in California, Pennsylvania or Rhode Island please contact lab for alternate testing.

Rejection Criteria
Bloody sample

Methodology
Immunoassay - Real-Time Quaking-Induced Conversion (RT-QulC)

Stability
CSF and Urine: Room Temperature: 24 hours; Refrigerated: 14 days; Frozen: Indefinitely

Reference Range
By report

Performed
Varies

Turnaround Time10-14 days
Test CodeCSFPR
CPT-4 Code (s)
83520, 0035U (RT-QulC)
LOINC Codes
Est Prob Prion Dis in Patient:   Not available  
RT-QulC (CSF)*:   Not available  
T-tau protein (CSF):   Not available  
14-3-3 protein (CSF):   31989-7  
Comment:   48767-8  

Warde
Medical
Laboratory