17-KETOSTEROIDS

Specimen Required
Collect all urine for 24 hours. Keep sample refrigerated during collection, mix well and send a 4.0 mL aliquot (3.0 mL minimum) refrigerated in a screw-capped plastic urine container.

Alternate Specimen
2 screw-capped plastic vials containing 20 mg Sulfamic acid. Call lab to order acid. Adequate refrigeration is the most important aspect of specimen preservation.

Methodology
Quantitative Spectrophotometry

Stability
Room Temperature: 4 hours; Refrigerated: 14 days; Frozen: 1 month

Reference Range
17-Ketosteroids - per 24 h
   Male   Female  
0-11 months:   0.0-1.0 mg/d   0.0-1.0 mg/d  
1-5 years:   1.0-2.0 mg/d   1.0-2.0 mg/d  
6-10 years:   1.0-4.4 mg/d   1.4-3.9 mg/d  
11-12 years:   1.3-8.5 mg/d   3.8-9.5 mg/d  
13-16 years:   3.4-9.8 mg/d   4.5-17.1 mg/d  
17-50 years:   5.3-17.6 mg/d   4.4-14.2 mg/d  
50+ years:   4.1-12.1 mg/d   3.2-10.6 mg/d  
Creatinine:   By Report  
Reference intervals for random urine samples (mg/L) are not available.
Note: A large number of substances may interfere with this test. Decreases may be caused by carbamazepine, cephaloridine, cephalothin, chlormerodrin, digoxin, glucose, metyrapone, promazine, propoxyphene, reserpine, and others. Increases may be caused by acetone, acetophenide, ascorbic acid, chloramphenicol, chlorothazide, chlorpromazine, cloxacillin, dexamethasone, erythromycin, ethinamate, etryptamine, methicillin, methyprylon, morphine, oleadomycin, oxacillin, penicillin, phenaglycodol, phenazopyridine, phenothiazine, piperidine, quinidine, secobarbital, spironolactone, and others.

Performed
Monday, Wednesday, Friday

Turnaround Time5-7 days
Test CodeU17KS
CPT-4 Code (s)
83586
LOINC Codes
17 Ketosteroids/volume   21038-5  
17 Ketosteroids, per 24 hr   6766-0  
Creatinine, urine/volume   2161-8  
Total volume   19153-6  
Creatinine urine/24 hr   2162-6  
Hours collected   30211-7  

Warde
Medical
Laboratory