ABL KINASE DOMAIN MUTATION IN CML, CELL-BASED
Specimen Required
Alternate Specimen
Rejection Criteria
Methodology
Stability
Reference Range
Performed
| Collect bone marrow (2.1 mL minimum) in EDTA tube. Send refrigerated. Specimen must arrive at the lab the day of collection due to short stability. Send Monday-Thursday only. |
Alternate Specimen
| Bone marrow: Sodium heparin | |||
| Whole blood: EDTA or sodium heparin |
Rejection Criteria
| Gross hemolysis, lipemia, frozen samples, clotted whole blood samples, clotted bone marrow samples. |
Methodology
| Nested Polymerase Chain Reaction | |||
| Real-Time Polymerase Chain Reaction | |||
| Sequencing |
Stability
| Room temperature: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable |
Reference Range
| See report |
Performed
| Sunday-Monday |
| 4-6 days | |||||||||
| ABLKD | |||||||||
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