ABL KINASE DOMAIN MUTATION IN CML, CELL-BASED

Specimen Required
Collect bone marrow (2.1 mL minimum) in EDTA tube. Send refrigerated. Specimen must arrive at the lab the day of collection due to short stability. Send Monday-Thursday only.

Alternate Specimen
Bone marrow: Sodium heparin
Whole blood: EDTA or sodium heparin

Rejection Criteria
Gross hemolysis, lipemia, frozen samples, clotted whole blood samples, clotted bone marrow samples.

Methodology
Nested Polymerase Chain Reaction
Real-Time Polymerase Chain Reaction
Sequencing

Stability
Room temperature: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable

Reference Range
See report

Performed
Sunday-Monday

Turnaround Time4-6 days
Test CodeABLKD
CPT-4 Code (s)
81170
ZB0R6
LOINC Codes
ABL Mutation, Cell-based   55135-8  
ABL Possible Mutations   55135-8  

Warde
Medical
Laboratory