ALDOSTERONE, URINE

Specimen Required
Collect 24 hour urine. Urine must be refrigerated during collection. Add 1.0 g boric acid/100 mL urine mix well and send 4.5 mL aliquot boric acid preserved urine (0.5 mL minimum) frozen in a screw-capped plastic urine container. Record total volume on test requisition and specimen label.

Alternate Specimen
6M HCl or Acetic acid preserved urine (pH adjusted to 2-4), refrigerate. Unpreserved urine frozen immediately after collection.

Methodology
Quantitative Radioimmunoassay

Stability
Room Temperature: 2 hours; Refrigerated (with preservative): 5 days; Frozen: 1 month

Reference Range
Aldosterone:
Normal diet:   6-25 µg/d  
Low salt diet:   17-44 µg/d  
High salt diet:   0-6 µg/d  
Normal urine values of aldosterone are dependent on sodium intake.
Normal sodium intake:   100-200 mEq  
Low sodium intake:   <25 mEq  
High sodium intake:   >200 mEq  
Creatinine (24-hour):   Male:   Female:  
   3-8 yrs: 140-700 mg/d   3-8 yrs:140-700 mg/d  
   9-12 yrs: 300-1300 mg/d   9-12 yrs: 300-1300 mg/d  
   13-17 yrs: 500-2300 mg/d   13-17 yrs: 400-1600 mg/d  
   18-50 yrs: 1000-2500 mg/d   18-50 yrs: 700-1600 mg/d  
   51-80 yrs: 800-2100 mg/d   51-80 yrs: 500-1400 mg/d  
   >=81 yrs: 600-2000 mg/d   >=81 yrs: 400-1300 mg/d  

Performed
Tuesday, Thursday, Saturday

Turnaround Time3-7 days
Test CodeUALDO
CPT-4 Code (s)
82088
LOINC Codes
Aldosterone, Urine   1765-7  
Creatinine, Urine - per volume   2161-8  
Creatinine, Urine - per 24h   2162-6  
Total volume   19153-6  
Hours collected   30211-7  

Warde
Medical
Laboratory