ALDOSTERONE/DIRECT RENIN RATIO

Components
Aldosterone (ALDOS), Direct Renin (DREN) and Ratio calculation. Please do not order ALDOS and DREN individually when ALDR is ordered.

Specimen Required
Aldosterone: Draw blood in a SST. Centrifuge, separate and send 1.0 mL serum (0.6 mL minimum) refrigerated in a screw-capped plastic vial. Label this tube "serum-aldosterone" and RENIN: Draw blood in 2 lavender EDTA tubes. Centrifuge, separate and send 1.5 mL plasma (1.0 mL minimum) frozen in a screw-capped plastic vial. CRITICAL FROZEN. Label this tube "Frozen Plasma-Renin". Also, please match sample requirement on label to correct sample type.

Alternate Specimen
Aldosterone: Serum: Red-top; Direct Renin: No alternate specimen

Rejection Criteria
Aldosterone: Plasma: gross hemolysis, gross lipemia; Renin: Hemolysis, icterus, gross lipemia, non-frozen samples, serum, plasma other than EDTA.

Methodology
Aldosterone: Chemiluminescence; Direct Renin: Chemiluminescence; Ratio: Calculation

Stability
Aldosterone: Room temperature: Unacceptable; Refrigerated: 5 days; Frozen: 1 month.
Renin: Room temperature: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month

Reference Range
Aldosterone: Upright: <39.2 ng/dL, Supine: <23.2 ng/dL; Aldosterone/Direct Renin Ratio: 0.1-3.7; Renin: 3.1-57.1 pg/mL

Performed
Monday, Wednesday, Thursday

Turnaround Time5 days
Test CodeALDR
CPT-4 Code (s)
82088, 84244
LOINC Codes
Aldosterone   1763-2  
Direct Renin   35570-1  
Aldosterone/Direct Renin Ratio   30894-0  

Warde
Medical
Laboratory