AMITRIPTYLINE

Components
Includes Nortriptyline

Specimen Required
Draw blood in a plain red-top tube. Centrifuge and separate from cells within 8 hours. Send 1.0 mL serum (0.5 mL minimum) refrigerated in a screw-capped plastic vial.

Alternate Specimen
Plasma: EDTA, oxalate or sodium fluoride

Rejection Criteria
SST

Methodology
High Performance Liquid Chromatography

Stability
Room Temperature: 48 hours; Refrigerated: 14 days; Frozen: 14 days

Reference Range
Amitriptyline + Nortriptyline
Therapeutic:   90–250 ng/mL  
Toxic:   >500 ng/mL  

Performed
Monday-Friday

Turnaround Time1-3 days
Test CodeAMITR
CPT-4 Code (s)
80335 (G0480)
LOINC Codes
3335-7

Warde
Medical
Laboratory