B-TYPE NATRIURETIC PEPTIDE (BNP)

Specimen Required
Draw blood in a lavender EDTA tube. Centrifuge, separate plasma from cells within 2 hours and send 2.0 mL plasma (0.5 mL minimum) frozen in a screw-capped plastic vial.

Rejection Criteria
Frozen whole blood, specimens frozen in separator tubes, hemolyzed specimens

Methodology
Quantitative Chemiluminescent Immunoassay

Stability
Room Temperature: 4 hours; Refrigerated: 4 hours; Frozen: 4 months

Reference Range
A cutoff of 100 pg/mL has been demonstrated to provide the maximal combination of sensitivity, specificity and negative predictive value for contributing to the diagnosis of congestive heart failure (CHF). A BNP value greater than 100 pg/mL is consistent with a diagnosis of CHF in the appropriate clinical setting. False-positive results are more common in females greater than 75 years of age. Blood concentrations of natriuretic peptides may also be elevated in patients with myocardial infarction and in patients who are candidates for or are undergoing renal dialysis.

Performed
Sunday-Saturday

Turnaround Time2-3 days
Test CodeBNPAR
CPT-4 Code (s)
83880
LOINC Codes
30934-4

Warde
Medical
Laboratory