COBALT, BLOOD

Specimen Required
Patient preparation: Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medication (upon the advice of their physician). Draw blood in a dark blue EDTA tube. Send 6.0 mL whole blood (0.5 mL minimum) room temperature in the original collection tube.

Rejection Criteria
Heparinized specimens. Frozen specimens. Clotted specimens.

Methodology
Quantitative Inductively Coupled Plasma - Mass Spectrometry

Stability
If the specimen is drawn and stored in the appropriate container the trace element values do not change with time.
Room Temperature: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Range
0.5 - 3.9 ug/L
Interpretive data: Elevated results may be due to skin or collection-related contamination, including the use of a noncertified metal-free collection/transport tube. If contamination concerns exist due to elevated levels of blood cobalt, confirmation with a second specimen collected in a certified metal-free tube is recommended. Blood cobalt levels can be used in the assessment of occupational exposure or toxic ingeston. Symptoms associated with cobalt toxicity vary based on route of exposure or toxic ingeston. Symptoms associated with cobalt toxicity vary based on route of exposure and may include cardiomyopathy, allergic dermatitis, pulmonary fibrosis, cough and dyspnea. Blood is the preferred specimen type for evaluating metal ion release from metal-on-mtal joint arthroplasty.

Performed
Tuesday, Friday

Turnaround Time5-7 days
Test CodeCOBLD
CPT-4 Code (s)
83018
LOINC Codes
5625-9

Warde
Medical
Laboratory