CORTISOL RESPONSE TO ACTH STIMULATION, SERUM

Specimen Required
For each timed specimen submitted each tube must be clearly marked with the time collected. Submit all specimens with one order. Draw morning baseline specimen in a red-top tube. Physician then administers 250 mcg cosyntropin. Draw additional specimens in red-top tubes at 15, 30, 60 minutes. Centrifuge each tube, remove serum from cells, and send 1.0 mL serum (0.1 mL minimum) refrigerated for each specimen. Each tube must be properly labeled with collection times.

Rejection Criteria
SST

Methodology
Liquid Chromatography - Tandem Mass Spectometry

Stability
Room temperature: 48 hours; Refrigerated: 7 days; Frozen: 2 years

Reference Range
Cortisol Baseline: 5-21 mcg/dL
Cortisol 15 minutes: 13-30 mcg/dL
Cortisol 30 minutes: 14-36 mcg/dL
Cortisol 60 minutes: 14-41 mcg/dL

Performed
Sunday-Friday

Turnaround Time4-6 days
Test CodeCORSI
CPT-4 Code (s)
82533 x 4
LOINC Codes
Cortisol Baseline:   Not available  
Cortisol 15 minutes:   Not available  
Cortisol 30 minutes:   Not available  
Cortisol 60 minutes:   Not available  

Warde
Medical
Laboratory