EPSTEIN-BARR VIRUS (EBV) SEROLOGY

Components
Antibody to Early Antigens, Antibody to Nuclear Antigen, IgG Antibody to Viral Capsid Antigen, IgM Antibody to Viral Capsid Antigen

Specimen Required
Draw blood in a SST. Centrifuge, separate and send 1.0 mL serum (0.5 mL minimum) refrigerated in a screw-capped plastic vial.

Alternate Specimen
Serum: Red-top

Rejection Criteria
Hemolysis, lipemia

Methodology
Chemiluminescent Immunoassay

Stability
Room Temperature: Unacceptable; Refrigerated: 48 hours; Frozen: 14 days

Reference Range
EBV-EA:     
   Negative:   <9.0 U/mL  
   Equivocal:   9.0-10.9 U/mL  
   Positive:   >=11.0 U/mL  
EBV-EBNA (IgG):
   Negative:   <18.0 U/mL  
   Equivocal:   18.0-21.9 U/mL  
   Positive:   >=22.0 U/mL  
EBV-VCA IgG:
   Negative:   <18.0 U/mL  
   Equivocal:   18.0-21.9 U/mL  
   Positive:   >=22.0 U/mL  
EBV-VCA IgM:     
   Negative:   <36.0 U/mL  
   Equivocal:   36.0-43.9 U/mL  
   Positive:   >=44.0 U/mL  

Performed
Monday-Friday

Turnaround Time3 days
Test CodeEBVS
CPT-4 Code (s)
86663, 86664, 86665 x 2
LOINC Codes
EBV-EA   24007-7  
EBV-EBNA (IgG)   31374-2  
EBV-VCA IgG   7885-7  
EBV-VCA IgM   7886-5  

Warde
Medical
Laboratory