EPSTEIN-BARR VIRUS (EBV) SEROLOGY

Test Documentation
Components
Antibody to Early Antigens, Antibody to Nuclear Antigen, IgG Antibody to Viral Capsid Antigen, IgM Antibody to Viral Capsid Antigen

Specimen Required
Draw blood in a SST. Centrifuge, separate and send 1.0 mL serum (0.5 mL minimum) refrigerated in a screw-capped plastic vial.

Alternate Specimen
Serum: Red-top

Rejection Criteria
Hemolysis, lipemia

Methodology
Chemiluminescent Immunoassay

Stability
Room Temperature: Unacceptable; Refrigerated: 48 hours; Frozen: 14 days

Reference Range
EBV-EA:     
   Negative:   <9.0 U/mL  
   Equivocal:   9.0-10.9 U/mL  
   Positive:   >=11.0 U/mL  
EBV-EBNA (IgG):
   Negative:   <18.0 U/mL  
   Equivocal:   18.0-21.9 U/mL  
   Positive:   >=22.0 U/mL  
EBV-VCA IgG:
   Negative:   <18.0 U/mL  
   Equivocal:   18.0-21.9 U/mL  
   Positive:   >=22.0 U/mL  
EBV-VCA IgM:     
   Negative:   <36.0 U/mL  
   Equivocal:   36.0-43.9 U/mL  
   Positive:   >=44.0 U/mL  

Performed
Monday-Friday

Turnaround Time3 days
Test CodeEBVS
CPT-4 Code (s)
86663, 86664, 86665 x 2
LOINC Codes
EBV-EA   22294-3  
EBV-EBNA (IgG)   7883-2  
EBV-VCA IgG   30339-6  
EBV-VCA IgM   7886-5  

Warde
Medical
Laboratory