ER/PR/HER2 WITH REFLEX to HER2 FISH

Test Documentation
Components
If result is 2+, HER2FISH is performed at an additional charge.

Specimen Required
Send formalin fixed (fixation between 6 and 48 hours is recommended) paraffin embedded tissue at room temperature. Please include a stained H & E slide and a pathology report. Information required in report: Physician identification, case and block number, specimen site, tissue processing used, fixative, time and duration of fixation and diagnosis.

Alternate Specimen
9 4 micron unstained sections of Poly-L-Lysine or silane coated slides

Rejection Criteria
Non-invasive tumors, blocks with insufficient tumor for testing.

Methodology
Immunohistochemical Assay (IHC)
Fluorescent in situ Hybridization (FISH)

Stability
Room Temperature: Indefinite; Refrigerated: Indefinite; Frozen: Not established

Reference Range
By report

Performed
Monday-Friday

Turnaround Time8-12 days
Test CodeHERN
CPT-4 Code (s)
88360 x 3
Add 88368 x 2 if FISH performed, at an additional charge.
LOINC Codes
16112-5
ER   14228-1  
PR   14230-7  
ER Interpretation   16112-5  
PR Interpretation   16113-3  
ER Stain Intensity   40556-3  
PR Stain Intensity   40557-1  
HER2 IHC   18474-7  
HER2 FISH   31150-6  

Warde
Medical
Laboratory