HELICOBACTER PYLORI ANTIGEN, STOOL

Components
Antimicrobials, proton pump inhibitors, and bismuth preparations are known to suppress H. pylori. Ingestion of these agents within two weeks of H. pylori testing may produce a false negative result due to decreased bacterial load.
Performance characteristics have not been established for watery, diarrheal stools, for pediatric populations (<18 years of age), and for asymptomatic patients.

Specimen Required
Patient Preparation: For initial diagnostic purposes no special preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained. To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure. This test is cleared for use with specimens from pediatric patients.
Collect 0.5 mL or 0.5 grams of semi-solid stool or 20 mm diameter stool and send frozen in a screw-capped polypropylene container. Please contact Warde lab for polypropylene screw-capped containers for shipping frozen stool. Polystyrene containers are unacceptable for frozen shipping.

Rejection Criteria
Watery, diarrheal stool, stool in preservative, transport media or swab.

Methodology
Immunoassay

Stability
Room Temperature: Unacceptable; Refrigerated: 72 hours; Frozen: 30 days

Reference Range
Not detected

Performed
Monday-Sunday

Turnaround Time3-5 days
Test CodeHPAG
CPT-4 Code (s)
87338
LOINC Codes
17780-8

Warde
Medical
Laboratory