HEMOGLOBINOPATHY EVALUATION

Test Documentation
Components
Detects hemoglobin variants including Hemoglobin S, Hemoglobin C, and others. Quantitates Hemoglobin A2 for thalassemia assessment.

Specimen Required
Draw blood in a lavender EDTA tube. Send 5.0 mL whole blood (1.0 mL minimum) refrigerated. Please supply CBC results with test requisition.

Alternate Specimen
Whole Blood: heparin, fluoride

Methodology
Capillary Electrophoresis
HPLC/gels as needed

Stability
Room Temperature: Unacceptable; Refrigerated: 7 days; Frozen: Unacceptable

Reference Range
A1:   96.5%-97.8%  
A2:   2.2%-3.2%  
Hgb F:
Newborn-1 month:   46.0%-81.0%  
2 months-4 months:   9.4%-61.0%  
4 months-12 months:   1.3%-22.0%  
1 Year-Adult:   <2%  

Performed
Monday-Friday

Turnaround Time3 days
Test CodeHGBE
CPT-4 Code (s)
83020
LOINC Codes
19146-0

Warde
Medical
Laboratory