IMMUNE COMPLEX DETECTION, (C1q Binding)

Test Documentation
Components
Immune complex assays measure extremely heterogeneous molecules that vary in size by order of magnitude. Therefore, there may be poor agreement between different techniques on a given sample. Warde Medical Laboratory does not recommend these assays for any specific diagnosis. They are not as sensitive as C-reactive protein (CRP) or erythrocyte sedimentation rate (ESR or Sed rate) for detecting and acute phase response. Further, immune complex assays are not as reliable as CH50, C3, C4 assays to detect complement activation.

Specimen Required
Draw blood in a plain red-top tube. Let sample clot 2 hours, centrifuge, separate and send 1.0 mL serum (0.3 mL minimum) frozen in a screw-capped plastic vial. CRITICAL FROZEN.

Methodology
Semi-quantitative Enzyme-linked Immunosorbent Assay

Stability
Room Temperature: 2 hours; Refrigerated: Unacceptable; Frozen: 14 days

Reference Range
<4 µgE/mL is considered negative for circulating complement binding immune complexes.

Performed
Monday, Thursday

Turnaround Time3-10 days
Test CodeC1QBA
CPT-4 Code (s)
86332
LOINC Codes
27831-7

Warde
Medical
Laboratory