LEAD AND ZINC PROTOPORPHYRIN, INDUSTRIAL EXPOSURE

Specimen Required
Draw blood in a dark blue EDTA tube. Send 7.0 mL whole blood (2.0 mL minimum) refrigerated.
A completed lead requisition must accompany sample.

Alternate Specimen
Whole blood: Lavender EDTA, K2EDTA

Rejection Criteria
Lead: Clotted samples
ZPP: Hemolyzed & clotted samples

Methodology
Atomic Absorption Spectrophotometry/Fluorometry

Stability
ZPP: Room Temperature: 8 days; Refrigerated: 8 weeks; Frozen: Unacceptable
Lead: Room temperature: 7 days; Refrigerated: 1 month; Frozen: Not recommended

Reference Range
COMPONENTS   REFERENCE INTERVAL   
Lead, Whole Blood   >15 years:   <5.0 mg/dL   
Zinc Protoporphyrin (ZPP), Whole Blood:   0-69 µmol/mol heme   
Zinc Protoporphyrin (ZPP), Whole Blood:   0-40 µg/dL   
Interpretive Data:
Action required for workers with elevated Lead Values OSHA, Occupational Exposure to Lead:
Blood Lead   Comment   
<5.0 ug/dL   No action required   
These results should be interpreted in the context of OSHA, CDC, and local and state occupational health requirements. Additional information is available through the following links:
cdc.gov/niosh/topics/ables/description.html
cdc.gov/niosh/topics/ables/pdfs/Reference%20Blood%20Levels%20for%20Adults-2015-12-18_508.pdf

Performed
Lead: Sunday-Friday
ZPP: Sunday, Tuesday, Thursday

Turnaround Time2-4 days
Test CodeZPPI
CPT-4 Code (s)
83655 (Lead), 84202 (Zinc Protoporphyrin)
LOINC Codes
Lead, whole blood   5671-3  
ZPP, umol/MOL HEME   29763-0  
ZPP, Whole blood   33007-6  

Warde
Medical
Laboratory