LIPOPROTEIN ELECTROPHORESIS

Specimen Required
Draw blood in a SST. Centrifuge, separate and send 2.0 mL serum (1.0 mL minimum) refrigerated in a screw-capped plastic vial. Patient should be fasting 8-12 hours prior to collection.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol, urine acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Alternate Specimen
Serum: Red-top

Methodology
Agarose Gel Electrophoresis

Stability
Room Temperature: 24 hours; Refrigerated: 7 days; Frozen: 14 days

Reference Range
By report

Performed
Wednesday

Turnaround Time7-10 days
Test CodeLIPE
CPT-4 Code (s)
82465, 83700, 84478
LOINC Codes
Cholesterol, Total   2093-3  
Triglycerides   2571-8  
Chylomicrons   2121-2  
Beta Lipoprotein   15122-5  
Pre-beta Lipoprotein   15123-3  
Alpha Lipoprotein   15121-7  
Serum, Appearance   11158-3  
Interpretation   8251-1  

Warde
Medical
Laboratory