MACROPROLACTIN

Specimen Required
Draw blood in a plain red-top tube. Centrifuge, separate and send 1.0 mL serum (0.6 mL minimum) frozen in a screw-capped plastic vial.

Alternate Specimen
Serum: SST

Rejection Criteria
Gross hemolysis

Methodology
Polyethylene Glycol (PEG) Precipitation followed by Electrochemiluminescent Immunoassay

Stability
Room Temperature: Unacceptable; Refrigerate: 14 days; Frozen: 180 days

Reference Range
Unprecipitated Prolactin/Total Prolactin Ratio: >50%
Total Prolactin:
Males:
<=18 years: Not established
>18 years: 4.0-15.2 ng/mL
Females:
>=18 years: Not established
>18 years: 4.8-23.3 ng/mL
Percent of the precipitated (complexed) prolactin fracton of the total prolactin <50% (considered negative for macroprolactin)

Performed
Monday-Saturday

Turnaround Time2-4 days
Test CodeMAPRL
CPT-4 Code (s)
84146 x 2
LOINC Codes
Prolactin, Unprecipitated, S   38926-2  
Prolactin, Total, S   2842-3  
Percent   51441-4  
Comment   48767-8  

Warde
Medical
Laboratory