MATERNAL SERUM ALPHA-FETOPROTEIN

Sample Reports
Sample Abnormal Report
Sample Normal Report

Test Documentation
Prenatal Screen Information Sheet

Components
Includes: Alpha-Fetoprotein (AFP)
Screens for neural tube defects (NTD). May be requested as a follow-up to First Trimester Screen.

Specimen Required
Draw blood in a plain red-top tube. Centrifuge, separate serum from cells within 2 hours of collection and send 1.0 mL serum (0.6 mL minimum) frozen within 48 hours in a screw-capped plastic vial. The following information must be submitted: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first day of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect pregnancy (NTD) for the patient. Sample should be collected between 15 weeks 0 days and 22 weeks 6 days gestation. Completed prenatal information sheet (supplied by Client Services) must accompany sample.

Alternate Specimen
Serum: SST

Rejection Criteria
Moderately hemolyzed specimens, lipemic specimens, plasma

Methodology
Chemiluminescent Immunometric Assay

Stability
Room Temperature: Unacceptable; Refrigerated: 48 hours; Frozen: 14 days

Reference Range
By report

Performed
Monday-Friday

Turnaround Time4 days
Test CodeMSAFP
CPT-4 Code (s)
82105

Warde
Medical
Laboratory