MULTIPLE SCLEROSIS (MS) PANEL

Test Documentation
Components
Includes CSF Protein Electrophoresis (Oligoclonal Bands), IgG (Serum and CSF), CSF IgG Index, Albumin (Serum and CSF), IgG Synthesis Rate. TEST REQUIRES BOTH SERUM AND CSF.

Specimen Required
Draw blood in a SST. Centrifuge blood, separate and send 1.0 mL serum (0.5 mL minimum) refrigerated in a screw-capped plastic vial. Send 1.0 mL CSF (0.5 mL minimum) refrigerated in a screw-capped plastic vial.

Alternate Specimen
Serum: Red-top and CSF

Methodology
Electrophoresis

Stability
Room Temperature: Unacceptable; Refrigerated: 7 days; Frozen: 14 days

Reference Range
Protein Electrophoresis (CSF)   Interpretive Report  
IgG (CSF)   0-3.4 mg/dL  
Albumin (CSF)   0-35 mg/dL  
CSF IgG Index   0.0-0.77  
IgG (serum)   700-1600 mg/dL  
Albumin (serum)   3500-5200 mg/dL  
IgG Synthesis Rate   0.0-3.00 mg/day  

Performed
Varies 2 x per week

Turnaround Time7 days
Test CodeMSP
CPT-4 Code (s)
82040, 82042, 82784 x 2, 83916
LOINC Codes
Panel   55121-8  
Protein Electrophoresis (CSF)   49295-9  
IgG (CSF)   2464-6  
Albumin (CSF)   1746-7  
CSF IgG Index   14117-6  
IgG (Serum)   38488-3  
Albumin (serum)   1751-7  
IgG Synthesis Rate   14116-8  

Warde
Medical
Laboratory