MULTIPLE SCLEROSIS (MS) PANEL

Components
Includes CSF Protein Electrophoresis (Oligoclonal Bands), IgG (Serum and CSF), IgG/Albumin Index (CSF), Albumin (Serum and CSF), IgG Synthesis Rate. TEST REQUIRES BOTH SERUM AND CSF.

Specimen Required
Draw blood in a SST. Centrifuge blood, separate and send 1.0 mL serum (0.5 mL minimum) refrigerated in a screw-capped plastic vial. Send 1.0 mL CSF (0.5 mL minimum) refrigerated in a screw-capped plastic vial.

Alternate Specimen
Serum: Red-top and CSF

Methodology
Electrophoresis

Stability
Room Temperature: Unacceptable; Refrigerated: 7 days; Frozen: 14 days

Reference Range
IgG (CSF)   0-3.4 mg/dL  
Albumin (CSF)   0-35 mg/dL  
CSF IgG Index   0.0-0.77  
IgG (serum)   700-1600 mg/dL  
Albumin (serum)   3500-5200 mg/dL  
IgG Synthesis Rate   0.0-3.00 mg/day  
IgG/Albumin Index (CSF)   0.00-0.77  

Performed
Varies 2 x per week

Turnaround Time7 days
Test CodeMSP
CPT-4 Code (s)
82040, 82042, 82784 x 2, 83916
LOINC Codes
Immunoglobulin G (IgG):   2465-3  
Albumin:   1751-7  
Immunoglobulin G, CSF:   2464-6  
Albumin, CSF:   1746-7  
IgG/Albumin Index (CSF):   2470-3  
IgG Synthesis Rate:   14116-8  
Oligoclonal Bands:   12782-9  

Warde
Medical
Laboratory