SEQUENTIAL SCREEN PART II (MATERNAL SERUM)

Sample Reports
Sample Abnormal Report
Sample Normal Report

Test Documentation
Prenatal Screen Information Sheet

Components
Inlcudes: Alpha-Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Unconjugated Estriol (UE3), and Inhibin A
Requires results from Sequential Screen Part I. Screens for Down syndrome, neural tube defects (NTD) & Trisomy 18.

Specimen Required
Draw blood in a plain red-top tube. Centrifuge, separate serum from cells within 2 hours of collection and send 1.0 mL serum (0.6 mL minimum) frozen within 48 hours in a screw-capped plastic tube. The following information must be submitted: ultrasound date with CRL and NT measurement, ultrasonographer certification number from NTQR or FMF, maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient. Sample should be collected between 15 weeks 0 days and 22 weeks 6 days gestation. Completed prenatal information sheet (supplied by Client Services) must accompany sample.

Alternate Specimen
Serum: SST

Rejection Criteria
Moderately hemolyzed specimens, lipemic specimens, plasma

Methodology
Chemiluminescent Immunoenzymatic Assay

Stability
Room Temperature: Unacceptable; Refrigerated; 48 hours; Frozen: 14 days

Reference Range
By report

Performed
Monday-Friday

Turnaround Time4 days
Test CodeSS2
CPT-4 Code (s)
82105, 82677, 84702, 86336 (or 81511)

Warde
Medical
Laboratory