Test Details
Mnemonic
AGALS
Ordering Code
3800353
CPT-4 Code(s)
82657
Specimen Information
Collect
Serum separator tube (SST)
Specimen Preparation
Centrifuge, separate serum from cells and send 2.0 mL serum in a screw capped plastic vial. Sex of patient is required for interpretation.
Alternate Specimen
Serum: Red top
Minimum Volume
0.2 mL
Transport Temperature
Frozen
Rejection Criteria
Gross hemolysis, gross lipemia, gross icterus
Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen: 14 days
Refrigerated: 24 hours
Frozen: 14 days
Methodology
Alpha-galactosidase is a lysosomal enzyme active at an acidic pH. The enzyme hydrolyzes artificial
substrates such as 4-methylumbelliferyl and alpha-D galactopyranoside. The 4-
methylumbelliferone liberated is measured by fluorometry
substrates such as 4-methylumbelliferyl and alpha-D galactopyranoside. The 4-
methylumbelliferone liberated is measured by fluorometry
Reference Range
0.074 - 0.457 U/L
Note: Results from this assay are not useful for
carrier determination. Carriers usually have levels
in the normal range.
Note: Results from this assay are not useful for
carrier determination. Carriers usually have levels
in the normal range.
Performing Laboratory
Mayo Clinic Laboratories
New York DOH Approval Status
Yes