Test Details
Mnemonic
BSEPL
Ordering Code
3600194
CPT-4 Code(s)
80338 (G0480)
Specimen Information
Patient Preparation
Timing of specimen collection: Pre-dose draw at steady state concentration.
Collect
Red top
Specimen Preparation
Centrifuge, separate serum from cells and freeze within 2 hours. Send 2.0 mL frozen in a screw capped plastic vial. CRITICAL FROZEN.
Alternate Specimen
Plasma: Lavender EDTA; sodium heparin, potassium oxalate or sodium fluoride.
Minimum Volume
0.5 mL
Transport Temperature
Critical frozen
Rejection Criteria
Serum separator tube (SST), sodium citrate, ACD B, Whole blood
Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Refrigerated: Unacceptable
Frozen: 14 days
Methodology
Quantitative Liquid Chromatography - Tandem Mass Spectrometry
Reference Range
Bupropion:
Therapeutic Range: 10-100 ng/mL
Toxic Level: ≥ 400 ng/mL
Hydroxybuproprion:
Therapeutic Range: 850 - 1500 ng/mL
Toxic Level: ≥ 2000 ng/mL
Therapeutic Range: 10-100 ng/mL
Toxic Level: ≥ 400 ng/mL
Hydroxybuproprion:
Therapeutic Range: 850 - 1500 ng/mL
Toxic Level: ≥ 2000 ng/mL
Performing Laboratory
ARUP
New York DOH Approval Status
Yes