WML Test Directory Update | August 2023 - Warde Medical Laboratory

Update Summary

Effective Date	Update Type	Name
08/22/2023	Inactivated/Replace Test	DNDSI – “DNA (DS) Antibody, Crithidia, IFA w/Refl” replaced by DNDS – “DNA (DS) Antibody, Crithidia, IFA w/Refl”	Jump to update
08/22/2023	Inactivated/Replace Test	MUSKE – “Muscle-Specific Kinase (MuSK) Antibody, IgG” replaced by MUSKG – “MuSK Ab, IgG by CBA-IFA wReflex to Titer, Serum”	Jump to update
08/08/2023	Inactivated Test	CNTH – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Throat”	Jump to update
08/08/2023	Inactivated Test	BBURV – “Borrelia burgdorferi VlsE1/pepC10 Abs, ELISA”	Jump to update
08/08/2023	Inactivated Test	CNREC – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Rectal”	Jump to update
08/22/2023	Updated Test	1433p – “14-3-3 eta Protein”	Jump to update
08/22/2023	Updated Test	BIACT – “Bile Acids, Total”	Jump to update
08/21/2023	Updated Test	MLH1 – “MLH1 Promoter Methylation”	Jump to update
08/21/2023	Updated Test	TBFCE – “TRG BF with RFLX to CHYLO”	Jump to update
08/21/2023	Updated Test	PRMET – “MGMT Promoter Methylation Det by ddPCR”	Jump to update
08/21/2023	Updated Test	MMMNG – “Myeloid Malignancies Mutation Panel by Next Gen. Sequencing”	Jump to update
08/21/2023	Updated Test	AH50 – “Alternative Complement Pathway Activity (AH50)”	Jump to update
08/21/2023	Updated Test	NARGC – “N-methyl-D-Aspartate Receptor Ab IgG CSF w Reflex to Titer”	Jump to update
08/21/2023	Updated Test	NMETD – “N-methyl-D-Asparate Receptor Ab, IgG, Serum with reflex to titer”	Jump to update
08/21/2023	Updated Test	UTPME – “Tapentadol, Urine, Quantitative”	Jump to update
08/21/2023	Updated Test	PRINS – “Proinsulin, Intact”	Jump to update
08/21/2023	Updated Test	MICAB – “Antimicrobial Susceptibility – MIC, Individual”	Jump to update
08/21/2023	Updated Test	ADB – “Dnase-B Antibody”	Jump to update
08/21/2023	Updated Test	TSHRA – “TRAb (TSH Receptor Antibody)”	Jump to update
08/21/2023	Updated Test	ADIPO – “Adiponectin”	Jump to update
08/14/2023	Updated Test	GLAGE – “Galactose-alpha-1,3-galactose IgE”	Jump to update
08/08/2023	Updated Test	CA153 – “CA 15-3”	Jump to update
08/08/2023	Updated Test	FER – “Ferritin”	Jump to update
08/01/2023	Updated Test	CVD – “Comprehensive Virus Detection”	Jump to update
08/01/2023	Updated Test	COPCR – “Chlamydia and Neisseria Testing by PCR”	Jump to update
08/01/2023	Updated Test	CHPCR – “Chlamydia Testing by PCR”	Jump to update
08/01/2023	Updated Test	GCPCR – “Neisseria gonorrheae Testing by PCR”	Jump to update
08/01/2023	Updated Test	TVPCR – “Trichomonas vaginalis Testing by PCR”	Jump to update

DNDSI – “DNA (DS) Antibody, Crithidia, IFA w/Refl” replaced by DNDS – “DNA (DS) Antibody, Crithidia, IFA w/Refl”

Effective Date 08/22/2023

Update Type Inactivated/Replace Test

Test Update View Test Update ›

Inactivated Test Details

Mnemonic

DNDSI

Ordering Code

3724220

CPT-4 Codes(s)

86255, plus 86256 if reflexed to titer, at additional cost

Replacement Test Details

Mnemonic

DNDS

Ordering Code

3000484

CPT-4 Codes(s)

86255

Specimen Information

Collect

Serum separator tube (SST)

Specimen Preparation

Centrifuge, separate serum from cells and send 1.0 mL serum refrigerated in a screw capped plastic vial.

Alternate Specimen

Serum, Red top

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Samples other than serum

Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: Undetermined

Methodology

Indirect Fluorescent Antibody

Reference Range

Negative

Performing Laboratory

Warde Medical Laboratory

Test Name	Ordering Code	Result Code	Component Name	LOINC Code	AOE Prompt
DNA (DS) Antibody, Crithidia, IFA w/Reflex	3000484
		3000484	DNA (DS) Antibody	Not available
		3000511	DNA Ab (ds) Crithidia, IFA	Not available	No
		3000512	DNA Ab (ds) Crithidia, Titer	Not available	No

MUSKE – “Muscle-Specific Kinase (MuSK) Antibody, IgG” replaced by MUSKG – “MuSK Ab, IgG by CBA-IFA wReflex to Titer, Serum”

Effective Date 08/22/2023

Update Type Inactivated/Replace Test

Test Update View Test Update ›

Inactivated Test Details

Mnemonic

MUSKE

Ordering Code

3600115

CPT-4 Codes(s)

86255, plus 86256 if reflexed, at an additional fee

Replacement Test Details

Mnemonic

MUSKG

Ordering Code

3600291

CPT-4 Codes(s)

86366, plus 86256 if reflexed to titer, at an additional fee

Specimen Information

Collect

Serum separator tube (SST)

Specimen Preparation

Centrifuge, separate serum from cells within 2 hours of collection and send 2.0 mL serum in a screw capped plastic vial.

Alternate Specimen

Red top

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Grossly lipemic, icteric or hemolyzed specimens

Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 1 month

Methodology

Semi-quantitative Cell-Based Indirect Fluorescent Antibody

Reference Range

<1:10

Performing Laboratory

ARUP

Test Name	Ordering Code	Result Code	Component Name	LOINC Code	AOE Prompt
MuSK Ab, IgG by CBA-IFA wReflex to Titer, Serum	3600291
		3600292	MuSK Ab IgG CBA IFA Screen, Serum	38362-0	No
		3600293	MuSK Ab IgG CBA IFA Titer, Serum	51763-1	No

CNTH – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Throat”

Effective Date 08/08/2023

Update Type Inactivated Test

Test Update View Test Update ›

Inactivated Test Details

Mnemonic

CNTH

Ordering Code

3435350

CPT-4 Codes(s)

87491, 87591

BBURV – “Borrelia burgdorferi VlsE1/pepC10 Abs, ELISA”

Effective Date 08/08/2023

Update Type Inactivated Test

Test Update View Test Update ›

Inactivated Test Details

Mnemonic

BBURV

Ordering Code

3600169

CPT-4 Codes(s)

86618

CNREC – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Rectal”

Effective Date 08/08/2023

Update Type Inactivated Test

Test Update View Test Update ›

Inactivated Test Details

Mnemonic

CNREC

Ordering Code

3435330

CPT-4 Codes(s)

87491, 87591

1433p – “14-3-3 eta Protein”

Effective Date 08/22/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Stability

Previous:	Updated To:
	Added: Room temperature: 7 days
	Added: Refrigerated: 7 days
Deleted:	Added: Frozen: 1 year

BIACT – “Bile Acids, Total”

Effective Date 08/22/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Collect

Previous:	Updated To:
Deleted:	Added: Serum separator tube (SST)

Specimen Preparation

Previous:	Updated To:
Deleted:	Added: Allow sample to clot completely at room temperature before centrifugation. Centrifuge and separate serum from cells within 1 hour of collection. Send 1.0 mL serum refrigerated in a screw capped plastic vial.

Alternate Specimen

Previous:	Updated To:
Deleted:	Added: Serum: Red top
	Added: Plasma: Lavender EDTA or Green lithium heparin

Minimum Volume

Previous:	Updated To:
Deleted:	Added: 0.5 mL

Transport Temperature

Previous:	Updated To:
Deleted:	Added: Refrigerated

Rejection Criteria

Previous:	Updated To:
Deleted:	Added: Hemolyzed sample or hemolysis, body fluids.

Stability

Previous:	Updated To:
	Added: Room temperature: 8 hours
	Added: Refrigerated: 14 days
Deleted:	Added: Frozen: 90 days

Methodology

Previous:	Updated To:
Deleted:	Added: Quantitative Enzyme Immunoassay

Reference Range

Previous:	Updated To:
Deleted:	Added: 0 - 10 mcgmol/L

Performing Laboratory

Previous:	Updated To:
Deleted:	Added: Quest SJC

Days Performed

Previous:	Updated To:
Deleted:	Added: Tuesday, Thursday, Saturday

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 3 - 6 days

Interface Map for

Test Name	Ordering Code	Result Code	Component Name	LOINC Code	AOE Prompt	Units
Bile Acids, Total	3717900
		3717900	Bile Acids, Total	14628-2	No

MLH1 – “MLH1 Promoter Methylation”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Minimum Volume

Previous:	Updated To:
Deleted:	Added: 5 slides (if using)

Rejection Criteria

Previous:	Updated To:
Deleted:	Added: Specimens fixed in alcohol or heavy metal fixative, decalcified specimens, less than 25% tumor

Days Performed

Previous:	Updated To:
Deleted:	Added: Varies

TBFCE – “TRG BF with RFLX to CHYLO”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Days Performed

Previous:	Updated To:
Deleted:	Added: Varies

PRMET – “MGMT Promoter Methylation Det by ddPCR”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Minimum Volume

Previous:	Updated To:
Deleted:	Added: 5 slides (if using)

Days Performed

Previous:	Updated To:
Deleted:	Added: Varies

MMMNG – “Myeloid Malignancies Mutation Panel by Next Gen. Sequencing”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Specimen Preparation

Previous:	Updated To:
Deleted:	Added: Send 3.0 mL whole blood in the original collection tube or a screw capped plastic vial. Separate specimens must be submitted when multiple tests are ordered.

Alternate Specimen

Previous:	Updated To:
	Added: Bone marrow: lavender EDTA or green sodium heparin
Deleted:	Added: Whole blood: Green sodium heparin

Minimum Volume

Previous:	Updated To:
Deleted:	Added: 1.0 mL for bone marrow, 1.5 for whole blood

Rejection Criteria

Previous:	Updated To:
Deleted:	Added: Serum, plasma, tissue, buccal brush or swab, grossly hemolyzed specimens.

Stability

Previous:	Updated To:
	Added: Room temperature: 72 hours
	Added: Refrigerated: 7 days
Deleted:	Added: Frozen: Unacceptable

AH50 – “Alternative Complement Pathway Activity (AH50)”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Update to test name.

Complement, Alt Pathway (AH50) -> Alternative Complement Pathway Activity (AH50)

Collect

Previous:	Updated To:
Deleted:	Added: Serum: Red top

Specimen Preparation

Previous:	Updated To:
Deleted:	Added: Allow specimen to clot for an hour at room temperature, then centrifuge and separate serum from cells within 2 hours of collection. Send 1.0 mL serum frozen in a screw capped plastic vial. CRITICAL FROZEN.

Alternate Specimen

Previous:	Updated To:
Deleted:	Added: no alternate specimens

Minimum Volume

Previous:	Updated To:
Deleted:	Added: 0.3 mL

Transport Temperature

Previous:	Updated To:
Deleted:	Added: CRITICAL FROZEN

Rejection Criteria

-Previous:
+Updated To:
+Added: Serum separator tube (SST)
+Added: Refrigerated or room temperature specimens.
+Added: Specimens other than serum.
+Added: Samples clotted at refrigerated temperature.
+Added: Specimens repeatedly frozen and thawed.
+Added: Grossly hemolyzed or lipemic.
-Deleted:
+Added: Icteric specimens

Stability

Previous:	Updated To:
	Added: Room temperature: Unacceptable
	Added: Refrigerated: Unacceptable
Deleted:	Added: Frozen (-70° C): 30 days

Methodology

Previous:	Updated To:
Deleted:	Added: Semi-quantitative Enzyme-Linked Immunosorbent Assay

Reference Range

Previous:	Updated To:
Deleted:	Added: >=31%

Days Performed

Previous:	Updated To:
Deleted:	Added: Sunday, Wednesday

NARGC – “N-methyl-D-Aspartate Receptor Ab IgG CSF w Reflex to Titer”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Days Performed

Previous:	Updated To:
Deleted:	Added: Sunday - Saturday

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 2 - 5 days

NMETD – “N-methyl-D-Asparate Receptor Ab, IgG, Serum with reflex to titer”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 2 - 5 days

UTPME – “Tapentadol, Urine, Quantitative”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Update to test name.

Tapentadol and Metabolite, Urine, Quantitative -> Tapentadol, Urine, Quantitative

Transport Temperature

Previous:	Updated To:
Deleted:	Added: Refrigerated

Reference Range

Previous:	Updated To:
Deleted:	Added: 50 ng/mL

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 3 - 10 days

PRINS – “Proinsulin, Intact”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Stability

Previous:	Updated To:
	Added: Room temperature: Unacceptable
	Added: Refrigerated: 24 hours
Deleted:	Added: Frozen: 2 months

Reference Range

Previous:	Updated To:
	Added: 0 - 17 years: Not Established
Deleted:	Added: 18 years and older: <= 7.2

MICAB – “Antimicrobial Susceptibility – MIC, Individual”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 4 - 9 days

ADB – “Dnase-B Antibody”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Stability

Previous:	Updated To:
	Added: Room temperature: 2 hours
	Added: Refrigerated: 8 days
Deleted:	Added: Frozen: 3 months

Days Performed

Previous:	Updated To:
Deleted:	Added: Sunday - Saturday

Turn-around Time

Previous:	Updated To:
Deleted:	Added: 3 - 6 days

TSHRA – “TRAb (TSH Receptor Antibody)”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Collect

Rejection Criteria

ADIPO – “Adiponectin”

Effective Date 08/21/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Stability

Methodology

Reference Range

GLAGE – “Galactose-alpha-1,3-galactose IgE”

Effective Date 08/14/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Collect

Specimen Preparation

Alternate Specimen

Minimum Volume

Transport Temperature

Rejection Criteria

Stability

Methodology

Reference Range

Performing Laboratory

Days Performed

Turn-around Time

CA153 – “CA 15-3”

Effective Date 08/08/2023

Update Type Updated Test

Test Update View Test Update ›

Performing Laboratory

FER – “Ferritin”

Effective Date 08/08/2023

Update Type Updated Test

Test Update View Test Update ›

Performing Laboratory

CVD – “Comprehensive Virus Detection”

Effective Date 08/01/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Specimen Preparation

-Previous:
+Updated To:
-Deleted:
+Added: Swab specimens in viral transport medium.
+Added: CSF and body fluids undiluted in sterile, leak-proof container - 3.0 mL (1.5 mL minimum).
+Added: Body fluids undiluted in sterile, leak-proof container - 1.0 mL (1.0 mL minimum).
+Added: Biopsy/tissue specimens should be ordered for Tissue Comprehensive Virus Detection (TCVD).
+Added: Stool in IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum) liquid stool or marble size solid stool.
+Added: Undiluted urine in an IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum).
+Added: Blood in EDTA (lavender top) tube - 3.0 mL (2.0 mL minimum).
+Added: Bone Marrow in EDTA - 1.0 mL (0.5 mL minimum).
+Added: For respiratory specimens order RCVD Respiratory Comprehensive Virus Detection

Rejection Criteria

-Previous:
+Updated To:
+Added: Rectal swabs and stool preserved in formalin, SAF, or PVA.
+Added: Stool specimens received with diapers, tissue paper, tongue depressors, sticks, and other objects.
+Added: Serum will not be tested due to decreased virus concentrations.
+Added: Urine in Grey-Top (boric acid) urine vacutainers. Specimens in Amplicor, EIA, Gen-Probe, or ProbeTec transport media.
+Added: Specimens in bacterial transport media, Stewart medium (Culturettes) and specimens in bacteriological blood culture media.
+Added: Dry swabs, wooden swabs, calcium alginate swabs, and swabs in gel transports.
+Added: Specimens received in non-sterile or leaking containers will not be tested.
-Deleted:
+Added: Respiratory specimens (Order RCVD)

COPCR – “Chlamydia and Neisseria Testing by PCR”

Effective Date 08/01/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Rejection Criteria

Updated To:

Specimens submitted with the white cleaning swab or with two swabs. Swabs in any media (e.g., M4, UTM, or Aptima media) other than the Alinity m Multi-Collect Collection Kit. Urine specimens where the liquid level in the urine transport tube does not fall within the clear fill window of the transport tube label (do not overfill). Urine specimens in sterile containers that have exceeded the 24 hour stability. Specimens collected in liquid cytology containers or media will not be tested.

Male urethral swab

CHPCR – “Chlamydia Testing by PCR”

Effective Date 08/01/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Rejection Criteria

Updated To:

Male urethral swab

GCPCR – “Neisseria gonorrheae Testing by PCR”

Effective Date 08/01/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Rejection Criteria

Updated To:

Male urethral swab

TVPCR – “Trichomonas vaginalis Testing by PCR”

Effective Date 08/01/2023

Update Type Updated Test

Test Update View Test Update ›

Specimen Information

Rejection Criteria

Updated To:

Male urethral swab

Previous:	Updated To:
	Added: Room temperature: 4 days
	Added: Refrigerated: 14 days
Deleted:	Added: Frozen: 28 days

August 2023 WML Test Directory Update

Update Summary

DNDSI – “DNA (DS) Antibody, Crithidia, IFA w/Refl” replaced by DNDS – “DNA (DS) Antibody, Crithidia, IFA w/Refl”

Inactivated Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

Replacement Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

Specimen Information

Collect

Specimen Preparation

Alternate Specimen

Minimum Volume

Transport Temperature

Rejection Criteria

Stability

Methodology

Reference Range

Performing Laboratory

Interface Map for DNDS

MUSKE – “Muscle-Specific Kinase (MuSK) Antibody, IgG” replaced by MUSKG – “MuSK Ab, IgG by CBA-IFA wReflex to Titer, Serum”

Inactivated Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

Replacement Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

Specimen Information

Collect

Specimen Preparation

Alternate Specimen

Minimum Volume

Transport Temperature

Rejection Criteria

Stability

Methodology

Reference Range

Performing Laboratory

Interface Map for MUSKG

CNTH – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Throat”

Inactivated Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

BBURV – “Borrelia burgdorferi VlsE1/pepC10 Abs, ELISA”

Inactivated Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

CNREC – “Chlamydia/Neisseria gonorrhoeae RNA, TMA, Rectal”

Inactivated Test Details

Mnemonic

Ordering Code

CPT-4 Codes(s)

1433p – “14-3-3 eta Protein”

Specimen Information

Stability

BIACT – “Bile Acids, Total”

Specimen Information

Collect

Specimen Preparation

Alternate Specimen

Minimum Volume

Transport Temperature

Rejection Criteria

Stability

Methodology

Reference Range

Performing Laboratory

Days Performed

Turn-around Time

Interface Map for

MLH1 – “MLH1 Promoter Methylation”

Specimen Information

Minimum Volume