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Update Summary

CSFPR – “14-3-3 Protein, CSF (Prion Disease)” replaced by CSFPD – “14-3-3 Protein, CSF (Prion Disease)”

Effective Date 10/08/2024
Update Type Inactivated/Replace Test
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Inactivated Test Details

Mnemonic

CSFPR

Ordering Code

3700101

CPT-4 Codes(s)

83520 x 2, 0035U

Replacement Test Details

Mnemonic

CSFPD

Ordering Code

3700116

CPT-4 Codes(s)

83520, 84394, 0035U

Turnaround Time
7 - 9 days
Performed
Varies
Legacy Code
CSFPD
Example Report

Specimen Information

Patient Preparation

The patient must be 12 years of age or older.

Collect

Cerebrospinal fluid (CSF)

Specimen Preparation

Collect Cerebrospinal fluid (CSF) - do not send the first 2.0 mL of CSF flow from tap. Send 2.0 mL CSF frozen immediately after collection, in a sterile screw capped plastic vial. Please call client service for a form. The ordering physician name and phone number are required by the National Prion Lab.

Alternate Specimen

Cerebrospinal fluid (CSF) collected in a SARSTEDT Polypropylene (PP), low binding sterile collection tube. CSF collected in a Sarstedt CSF false-bottom tube.

Minimum Volume

1.0 mL

Transport Temperature

CRITICAL FROZEN

Rejection Criteria

Bloody and insufficient sample quantity. Samples that are colored or contain blood cannot be performed for RT-QulC and 14-3-3 GAMMA.

Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: Indefinitely

Methodology

Qualitative Enzyme-Linked Immunosorbent Assay
more

Reference Range

RT-QuIC (CSF): No Change
T-tau protein (CSF): No Change
14-3-3 GAMMA (CSF): 173 - 1999 AU/mL
Likelihood of prion disease: No Change
more

Performing Laboratory

Quest
more

New York DOH Approval Status

Yes
more

Interface Map for CSFPD

Test Name Ordering Code Result Code Component Name LOINC Code AOE Prompt Units
14-3-3 Protein, CSF (Prion Disease)3700116
3700102 Likelihood of prion diseaseNo
3700104 T-tau protein (CSF)30160-6No
3700105 14-3-3 GAMMA (CSF) 31989-7No
3700103RT-QulC (CSF)*97503-7No
3700117Specimen ConditionNo
3700118 Reviewed and Approved by: No

ZPP – “Zinc Protoporphyrin” replaced by ZPPWB – “Zinc Protoporphyrin (ZPP), Whole Blood”

Effective Date 11/12/2024
Update Type Inactivated/Replace Test
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Inactivated Test Details

Mnemonic

ZPP

Ordering Code

1001550

CPT-4 Codes(s)

84202

Replacement Test Details

Mnemonic

ZPPWB

Ordering Code

3600422

CPT-4 Codes(s)

84202

Turnaround Time
3 - 6 days
Performed
Monday - Friday
Legacy Code
ZPPWB
Example Report

Specimen Information

Collect

Lavender EDTA

Specimen Preparation

Send 3.0 mL whole blood in the original collection tube.

Alternate Specimen

Whole Blood: Royal blue (K2EDTA), Royal blue (NaHep), Tan (K2EDTA), Pink (K2EDTA).

Minimum Volume

0.2 mL

Transport Temperature

Refrigerated

Rejection Criteria

Hemolyzed, clotted or frozen samples

Stability

Room temperature: 30 hours
Refrigerated: 5 weeks
Frozen: Unacceptable

Methodology

Quantitative Hematofluorometry
more

Reference Range

0-69 μmol ZPP/ mol Hem
more

Performing Laboratory

ARUP
more

New York DOH Approval Status

Yes
more

Interface Map for ZPPWB

Test Name Ordering Code Result Code Component Name LOINC Code AOE Prompt Units
Zinc Protoporphyrin (ZPP), Whole Blood3600422
3600422Zinc Protoporphyrin (ZPP), Whole Blood 29763-0No

MBMET – “Methyl Bromide Metabolite, Serum/Plasma”

Effective Date 10/01/2024
Update Type Inactivated Test
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Inactivated Test Details

Mnemonic

MBMET

Ordering Code

3600043

CPT-4 Codes(s)

82542

RSVAB – “RSV Antibody”

Effective Date 10/01/2024
Update Type Inactivated Test
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Notes

Suggested alternative is a respiratory sample with Warde test RVPCR: Respiratory Syncytial Virus (RSV) PCR.

Inactivated Test Details

Mnemonic

RSVAB

Ordering Code

3509740

CPT-4 Codes(s)

86756

CYSUP – “Cytology, SurePathLiquid-Based Pap Test and HPV”

Effective Date 10/21/2024
Update Type Inactivated Test
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HIVBL – “Human Immunodeficiency Virus 1 (HIV-1) Qualitative by NAAT”

Effective Date 10/21/2024
Update Type Inactivated Test
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Inactivated Test Details

Mnemonic

HIVBL

Ordering Code

3600041

CPT-4 Codes(s)

87535

SPPAP – “Cytology, SurePath Liquid-Based Pap Test”

Effective Date 10/21/2024
Update Type Inactivated Test
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VB7 – “Biotin (Vitamin B7)”

Effective Date 10/22/2024
Update Type Updated Test
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Notes

Update to stability

Stability:

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 14 days

Test Details

Mnemonic

VB7

Ordering Code

3721040

CPT-4 Codes(s)

84591

WML Test Directory Update | October 2024 | Warde Medical Laboratory Page