Inactivated/Replace Test
Effective Date
02/06/2024
Included in Report
Replacement Test
AGAS – “Alpha-galactosidase, Serum” replaced by AGALS – “Alpha-Galactosidase, Serum”
Back to Test UpdatesInactivated/Replace Test
Notes
Mayo # AGAS moving to MAYO # AGAS
Rebuild due to changes in resulting field, also changes to specimen requirements, TAT, and days performed.
Inactivated Test Details
Mnemonic
AGAS
Ordering Code
3805600
CPT-4 Codes(s)
82657
Replacement Test Details
Mnemonic
AGALS
Ordering Code
3800353
CPT-4 Codes(s)
82657
Turnaround Time
6 - 10 days
Performed
Tuesday, Friday
Legacy Code
AGALS
Example Report
Specimen Information
Collect
Serum separator tube (SST)
Specimen Preparation
Centrifuge, separate serum from cells and send 2.0 mL serum in a screw capped plastic vial. Sex of patient is required for interpretation.
Alternate Specimen
Serum: Red top
Minimum Volume
0.2 mL
Transport Temperature
Frozen
Rejection Criteria
Gross hemolysis, gross lipemia, gross icterus
Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen: 14 days
Refrigerated: 24 hours
Frozen: 14 days
Methodology
Alpha-galactosidase is a lysosomal enzyme active at an acidic pH. The enzyme hydrolyzes artificial substrates such as 4-methylumbelliferyl and alpha-D galactopyranoside. The 4-methylumbelliferone liberated is measured by fluorometry.
Reference Range
0.074 - 0.457 U/L
Note: Results from this assay are not useful for carrier determination.
Carriers usually have levels in the normal range.
Note: Results from this assay are not useful for carrier determination.
Carriers usually have levels in the normal range.
Performing Laboratory
MAYO
New York DOH Approval Status
Yes