Inactivated/Replace Test
Effective Date
11/28/2023
Included in Report
Replacement Test
CVD – “Comprehensive Virus Detection” replaced by CVP – “Comprehensive Virus Panel”
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Inactivated Test Details
Mnemonic
CVD
Ordering Code
3099000
CPT-4 Codes(s)
Depending on specimen source, testing may include: 87798 Adenovirus PCR 87496 CMV PCR 87498 Enterovirus PCR 87529 x 2 HSV1 and HSV2 PCR 87502 Norovirus 1 & 2 87631 Rhinovirus PCR 87634 VZV PCR
Replacement Test Details
Mnemonic
CVP
Ordering Code
3000846
CPT-4 Codes(s)
Varies: Adenovirus PCR 87798; CMV PCR 87496; Enterovirus PCR 87498; HSV1/2 PCR 87529 x 2; Norovirus 1/2 87798 x 2; Rhinovirus PCR 87798; VZV PCR 87798
Specimen Information
Collect
Variable specimen types
Specimen Preparation
Swab specimens in viral transport medium.
CSF and body fluids undiluted in sterile, leak-proof container - 3.0 mL (1.5 mL minimum).
Body fluids undiluted in sterile, leak-proof container - 1.0 mL (1.0 mL minimum).
Biopsy/tissue specimens should be ordered for Tissue Comprehensive Virus Detection (TCVD).
Stool in IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum) liquid stool or marble
size solid stool.
Undiluted urine in an IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum).
Blood in EDTA (lavender top) tube - 3.0 mL (2.0 mL minimum).
Bone Marrow in EDTA - 1.0 mL (0.5 mL minimum).
For respiratory specimens order RCVP Respiratory Comprehensive Virus Panel
CSF and body fluids undiluted in sterile, leak-proof container - 3.0 mL (1.5 mL minimum).
Body fluids undiluted in sterile, leak-proof container - 1.0 mL (1.0 mL minimum).
Biopsy/tissue specimens should be ordered for Tissue Comprehensive Virus Detection (TCVD).
Stool in IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum) liquid stool or marble
size solid stool.
Undiluted urine in an IATA-approved screw-capped container - 2.0 mL (1.0 mL minimum).
Blood in EDTA (lavender top) tube - 3.0 mL (2.0 mL minimum).
Bone Marrow in EDTA - 1.0 mL (0.5 mL minimum).
For respiratory specimens order RCVP Respiratory Comprehensive Virus Panel
Alternate Specimen
Stool in Cary Blair medium.
The Laboratory Director or Supervisor must approve testing of specimens other than those listed.
The Laboratory Director or Supervisor must approve testing of specimens other than those listed.
Minimum Volume
Determined by specimen type
Transport Temperature
Varies by specimen type, see stability
Rejection Criteria
Rectal swabs and stool preserved in formalin, SAF, or PVA.
Stool specimens received with diapers, tissue paper, tongue depressors, sticks, and other objects.
Serum will not be tested due to decreased virus concentrations.
Urine in Grey-Top (boric acid) urine vacutainers. Specimens in Amplicor, EIA, Gen-Probe, or ProbeTec transport media.
Specimens in bacterial transport media, Stewart medium (Culturettes) and specimens in bacteriological blood culture media.
Dry swabs, wooden swabs, calcium alginate swabs, and swabs in gel transports.
Specimens received in non-sterile or leaking containers will not be tested.
Respiratory specimens (Order RCVP)
Stool specimens received with diapers, tissue paper, tongue depressors, sticks, and other objects.
Serum will not be tested due to decreased virus concentrations.
Urine in Grey-Top (boric acid) urine vacutainers. Specimens in Amplicor, EIA, Gen-Probe, or ProbeTec transport media.
Specimens in bacterial transport media, Stewart medium (Culturettes) and specimens in bacteriological blood culture media.
Dry swabs, wooden swabs, calcium alginate swabs, and swabs in gel transports.
Specimens received in non-sterile or leaking containers will not be tested.
Respiratory specimens (Order RCVP)
Stability
Room temperature (18-25°C): 4 hours
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 7 days
Frozen (-70°C): 3 months
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 7 days
Frozen (-70°C): 3 months
Methodology
Source-driven panels. Polymerase Chain Reaction
Reference Range
Negative
Performing Laboratory
Warde Medical Laboratory