JAK2X – “JAK2 with reflex to NGS for ex12/CALR/MPL”

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New Test

Effective Date

01/06/2026

Included in Report

WML Test Directory Update | December 2025

Updated Test

JAK2 with reflex to NGS for ex12/CALR/MPL

Test Details

Mnemonic

JAK2X

Ordering Code

3000924

CPT-4 Codes(s)

81270 plus other CPTs if reflex testing is performed, at additional cost

Turnaround Time
7 - 14 days
Performed
Monday - Friday
Legacy Code
JAK2X
Example Report Negative
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Example Report Positive
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Specimen Information

Click here for additional information about choosing a molecular test for myeloproliferative neoplasm diagnosis.

Collect

Whole Blood EDTA Lavender

Specimen Preparation

Send 1.0 mL whole blood in a screw capped plastic vial.

Alternate Specimen

Bone Marrow

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Serum, plasma, tissue, buccal brush or swab, grossly hemolyzed specimens

Stability

Room temperature: 3 days
Refrigerated: 7 days
Frozen: 30 days

Methodology

Targeted Next Generation Sequencing
more

Reference Range

See report
more

Performing Laboratory

Warde Medical Laboratory
more

New York DOH Approval Status

No
more

Interface Map for JAK2X

Test Name Ordering Code Result Code Component Name LOINC Code AOE Prompt Units
JAK2 with reflex to NGS for ex12/CALR/MPL3000924
3000926Specimen Source31208-2 No
3000927JAK2 V617F Mutation by PCR43399-5No
3000928 Percent of WBCs with V617F Mutation 53761-3 No
3000929 JAK2 V617F Mutation by NGS 43399-5No
3000931 JAK2 Exon 12 Mutation 55300-8 No
3000932CALR Exon 9 Mutation77174-1 No
3000933 MPL Exon 10 Mutation 62947-7 No
3000934 CSF3R Mutation 92674-1No
3000936 Variant 1 Information48005-3 No
3000937 Variant 2 Information48005-3No
3000938Interpretation50398-7 No
3000939Assay Info8266-9No

The CPT codes provided are for general informational purposes only and are based on an interpretation of AMA guidance. It is the sole responsibility of the billing party to determine CPT codes. Any questions regarding coding should be directed to the paying party.

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