Inactivated/Replace Test
Effective Date
01/24/2023
Included in Report
Replacement Test
MGPMD – “MGMT Promoter Methylation Detection” replaced by PRMET – “MGMT Promoter Methylation Det by ddPCR”
Back to Test UpdatesInactivated/Replace Test
Inactivated Test Details
Mnemonic
MGPMD
Ordering Code
3600174
CPT-4 Codes(s)
81287
Replacement Test Details
Mnemonic
PRMET
Ordering Code
3600217
CPT-4 Codes(s)
81287
Specimen Information
Collect
Tumor tissue
Specimen Preparation
Send formalin-fixed tissue and/or paraffin embedded tissue. Send tissue block or 5 unstained 5-micron slides. Protect from excessive heat. Tissue block will be returned after testing. Please include pathology report.
If sending multiple samples, please indicate that the ARUP pathologist should choose the
specimen most appropriate for testing, or submit individual orders for each sample submitted.
If sending multiple samples, please indicate that the ARUP pathologist should choose the
specimen most appropriate for testing, or submit individual orders for each sample submitted.
Minimum Volume
3 slides
Transport Temperature
Room temperature
Rejection Criteria
Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or
B-5). Decalcified specimens. Less than 25 percent tumor.
B-5). Decalcified specimens. Less than 25 percent tumor.
Stability
Room Temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Droplet Digital PCR (ddPCR)
Reference Range
See report
Performing Laboratory
ARUP
New York DOH Approval Status
No