Inactivated/Replace Test
Effective Date
04/29/2025
Included in Report
Replacement Test
UPORA – “Porphyrins Fraction and Quant Ur” replaced by UPO24 – “Porphyrins, Fractionated, Quant, 24-Hour Urine”
Back to Test UpdatesInactivated/Replace Test
Inactivated Test Details
Mnemonic
UPORA
Ordering Code
3687300
CPT-4 Codes(s)
84120
Replacement Test Details
Mnemonic
UPO24
Ordering Code
3400983
CPT-4 Codes(s)
84120
Turnaround Time
3 - 7 days
Performed
Tuesday - Saturday
Legacy Code
UPO24
Example Report
Specimen Information
Collect
24 hour urine, refrigerate and protect from light during collection.
Specimen Preparation
Mix well and send 2.0 mL urine in an amber screw capped plastic vial.
PROTECT FROM LIGHT. Record 24 hour urine volume on test requisition and specimen label.
PROTECT FROM LIGHT. Record 24 hour urine volume on test requisition and specimen label.
Alternate Specimen
Urine collected in a 5 g sodium carbonate container
Minimum Volume
1.0 mL
Transport Temperature
Refrigerated
Rejection Criteria
Received room temperature, Not protected from light, pH <4.0
Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
High Performance Liquid Chromatography (HPLC)
Reference Range
Uroporphyrin I 4.1-22.4 mcg/24 h
Uroporphyrin III 0.7-7.4 mcg/24 h
Heptacarboxyporphyrin ≤3.3 mcg/24 h
Hexacarboxyporphyrin ≤10 mcg/24 h
Pentacarboxyporphyrin ≤4.6 mcg/24 h
Coproporphyrin I 7.1-48.7 mcg/24 h
Coproporphyrin III 11.0-148.5 mcg/24 h
Total Porphyrins 35.0-210.7 mcg/24 h
Uroporphyrin III 0.7-7.4 mcg/24 h
Heptacarboxyporphyrin ≤3.3 mcg/24 h
Hexacarboxyporphyrin ≤10 mcg/24 h
Pentacarboxyporphyrin ≤4.6 mcg/24 h
Coproporphyrin I 7.1-48.7 mcg/24 h
Coproporphyrin III 11.0-148.5 mcg/24 h
Total Porphyrins 35.0-210.7 mcg/24 h
Performing Laboratory
Quest
New York DOH Approval Status
Yes