Test Details

Mnemonic

CSFPD

Ordering Code

3700116

CPT-4 Code(s)

83520 x2, 0035U

Specimen Information

Patient Preparation

The patient must be 12 years of age or older.

Collect

Cerebrospinal fluid (CSF)

Specimen Preparation

Collect Cerebrospinal fluid (CSF) - do not send the first 2.0 mL of CSF flow from tap. Send 2.0 mL CSF frozen immediately after collection, in a sterile screw capped plastic vial. Please call client service for a form. The ordering physician name and phone number are required by the National Prion Lab.

Alternate Specimen

Cerebrospinal fluid (CSF) collected in a SARSTEDT Polypropylene (PP), low binding sterile collection tube. CSF collected in a Sarstedt CSF false-bottom tube.

Minimum Volume

1.0 mL

Transport Temperature

CRITICAL FROZEN

Rejection Criteria

Bloody and insufficient sample quantity. Samples that are colored or contain blood cannot be performed for RT-QulC and 14-3-3 GAMMA.

Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: Indefinitely

Methodology

Qualitative Enzyme-Linked Immunosorbent Assay
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Reference Range

RT-QuIC (CSF): No Change
T-tau protein (CSF): No Change
14-3-3 GAMMA (CSF): 173 - 1999 AU/mL
Likelihood of prion disease: No Change
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Performing Laboratory

Quest
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New York DOH Approval Status

Yes
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