Test Details
Mnemonic
CSFPD
Ordering Code
3700116
CPT-4 Code(s)
83520 x2, 0035U
Specimen Information
Patient Preparation
The patient must be 12 years of age or older.
Collect
Cerebrospinal fluid (CSF)
Specimen Preparation
Collect Cerebrospinal fluid (CSF) - do not send the first 2.0 mL of CSF flow from tap. Send 2.0 mL CSF frozen immediately after collection, in a sterile screw capped plastic vial. Please call client service for a form. The ordering physician name and phone number are required by the National Prion Lab.
Alternate Specimen
Cerebrospinal fluid (CSF) collected in a SARSTEDT Polypropylene (PP), low binding sterile collection tube. CSF collected in a Sarstedt CSF false-bottom tube.
Minimum Volume
1.0 mL
Transport Temperature
CRITICAL FROZEN
Rejection Criteria
Bloody and insufficient sample quantity. Samples that are colored or contain blood cannot be performed for RT-QulC and 14-3-3 GAMMA.
Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: Indefinitely
Refrigerated: Unacceptable
Frozen: Indefinitely
Methodology
Qualitative Enzyme-Linked Immunosorbent Assay
Reference Range
RT-QuIC (CSF): No Change
T-tau protein (CSF): No Change
14-3-3 GAMMA (CSF): 173 - 1999 AU/mL
Likelihood of prion disease: No Change
T-tau protein (CSF): No Change
14-3-3 GAMMA (CSF): 173 - 1999 AU/mL
Likelihood of prion disease: No Change
Performing Laboratory
Quest
New York DOH Approval Status
Yes