Test Details

Mnemonic

PBKQN

Ordering Code

3092740

CPT-4 Code(s)

87799

Specimen Information

Collect

Lavender EDTA

Specimen Preparation

Centrifuge and separate plasma from cells within 8 hours of collection. Send 2.0 mL plasma frozen in a screw capped plastic vial. Dedicated specimens are required. Specimens used in other assays will not be tested.

Minimum Volume

1.0 mL

Transport Temperature

Frozen

Rejection Criteria

Serum specimens, heparinized specimens, specimens in any gel-based separation media, shared specimens, specimens submitted to repeated freeze-thaw cycles, specimens received in non-sterile or leaking containers, specimens that do not meet the storage/handling conditions criteria above

Stability

Room temperature: 8 hours
Refrigerated: 3 days
Frozen (-20°C): 30 days
Frozen (-70°C): 6 months

Methodology

This test utilizes a polymerase chain reaction to amplify sequences from the VP1 regions of the BK virus genome. Real-time detection and quantification are used to determine the viral copy number. The analytical measurement range is 125 to 5 million copies/mL (2.10 to 6.70 log(10) copies/mL). The qualitative limit of detection is 100 copies/mL (2.00 log(10) copies/mL).
Specimens reported as "DETECTED" but <125 copies/mL contain detectable levels of BK virus DNA but the viral load is below the limit of quantitation. A "NOT DET" (NOT detected result does not rule out infection.
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Reference Range

BKV QUAL: Not detected (NOT DET)
BKV QUANT: <125 copies/mL
Log BKV: <2.10 log(10) copies/mL
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Performing Laboratory

Warde Medical Laboratory
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New York DOH Approval Status

No
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