Test Details

Mnemonic

CORSI

Ordering Code

3429600

CPT-4 Code(s)

82533 x 4

Specimen Information

Collect

Red top (4)

Specimen Preparation

For each timed specimen submitted each tube must be clearly marked with the time collected. Submit all specimens with one order. Draw morning baseline specimen in a red top tube. Physician then administers 250 mcg cosyntropin. Draw additional specimens in red top tubes at 15, 30, 60 minutes. Centrifuge each tube, remove serum from cells and send 1.0 mL serum refrigerated for each specimen. Each tube must be properly labeled with collection times.

Minimum Volume

0.2 mL per timed specimen

Transport Temperature

Refrigerated

Rejection Criteria

Serum separator tube (SST), gross hemolysis

Stability

Room temperature: 14 days
Refrigerated: 21 days
Frozen: 1 year

Methodology

Liquid Chromatography/Tandem Mass Spectometry
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Reference Range

Cortisol Baseline: 5 - 21 mcg/dL
Cortisol 15 minutes: 13 - 30 mcg/dL
Cortisol 30 minutes: 14 - 36 mcg/dL
Cortisol 60 minutes: 14 - 41 mcg/dL
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Performing Laboratory

Quest SJC
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