Test Details
Mnemonic
CRY
Ordering Code
2000760
CPT-4 Code(s)
82595 cryoglobulin, 82585 cryoglobulin; if a cryoglobulin is present, it is characterized by immunofixation at no additional cost
Specimen Information
Collect
Cryoglobulin - Red top
Cryofibrinogen - Light blue sodium citrate
Cryofibrinogen - Light blue sodium citrate
Specimen Preparation
Cryoglobulin: Draw 5.0 mL of blood into a prewarmed (37°C) red top tube. Allow blood to clot at 37°C. Centrifuge at 37°C or ambient temperature. Do not use a refrigerated centrifuge. Keep sample at 37°C until after separation of serum from red blood cells. Send 3.0 mL of serum in a screw capped plastic vial.
Cryofibrinogen: Draw blood into a prewarmed (37°C) light blue sodium citrate tube. Centrifuge
at 37°C or ambient temperature. Do not use a refrigerated centrifuge. Send 2.0 mL of plasma in
a screw capped plastic vial.
Cryofibrinogen: Draw blood into a prewarmed (37°C) light blue sodium citrate tube. Centrifuge
at 37°C or ambient temperature. Do not use a refrigerated centrifuge. Send 2.0 mL of plasma in
a screw capped plastic vial.
Minimum Volume
Cryofibrinogen: 1.0 mL; Cryoglobulin: 2.0 mL
Transport Temperature
Refrigerated
Rejection Criteria
Cryoglobulin: Plasma; Serum separator tube (SST); Grossly hemolyzed or lipemic specimens.
Cryofibrinogen: Serum; Heparanized plasma; Grossly hemolyzed or lipemic specimens
Cryofibrinogen: Serum; Heparanized plasma; Grossly hemolyzed or lipemic specimens
Stability
After proper sample collection and processing.
Room temperature: Undetermined
Refrigerated: 7 days
Frozen: 30 days
Room temperature: Undetermined
Refrigerated: 7 days
Frozen: 30 days
Methodology
Precipitation
Reference Range
Cryoglobulin: Absent
Cryofibrinogen: Absent
If a cryoprecipitate is present, a cryocrit (quantitation)
will be performed at no additional charge.
Cryofibrinogen: Absent
If a cryoprecipitate is present, a cryocrit (quantitation)
will be performed at no additional charge.
Performing Laboratory
Warde Medical Laboratory
New York DOH Approval Status
Yes