Test Details

Mnemonic

CRY

Ordering Code

2000760

CPT-4 Code(s)

82595 cryoglobulin, 82585 cryoglobulin; if a cryoglobulin is present, it is characterized by immunofixation at no additional cost

Specimen Information

Collect

Cryoglobulin - Red top
Cryofibrinogen - Light blue sodium citrate

Specimen Preparation

Cryoglobulin: Draw 5.0 mL of blood into a prewarmed (37°C) red top tube. Allow blood to clot at 37°C. Centrifuge at 37°C or ambient temperature. Do not use a refrigerated centrifuge. Keep sample at 37°C until after separation of serum from red blood cells. Send 3.0 mL of serum in a screw capped plastic vial.
Cryofibrinogen: Draw blood into a prewarmed (37°C) light blue sodium citrate tube. Centrifuge
at 37°C or ambient temperature. Do not use a refrigerated centrifuge. Send 2.0 mL of plasma in
a screw capped plastic vial.

Minimum Volume

Cryofibrinogen: 1.0 mL; Cryoglobulin: 2.0 mL

Transport Temperature

Refrigerated

Rejection Criteria

Cryoglobulin: Plasma; Serum separator tube (SST); Grossly hemolyzed or lipemic specimens.
Cryofibrinogen: Serum; Heparanized plasma; Grossly hemolyzed or lipemic specimens

Methodology

Precipitation
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Reference Range

Cryoglobulin: Absent
Cryofibrinogen: Absent
If a cryoprecipitate is present, a cryocrit (quantitation)
will be performed at no additional charge.
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Performing Laboratory

WARDE MEDICAL LABORATORY
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New York DOH Approval Status

Yes
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