Test Details

Mnemonic

ZPPI

Ordering Code

1001560

CPT-4 Code(s)

83655 (Lead), 84202 (Zinc Protoporphyrin)

Specimen Information

Collect

Dark blue trace element EDTA

Specimen Preparation

Send 7.0 mL whole blood refrigerated. PROTECT FROM LIGHT.
A completed lead requisition must accompany sample.

Alternate Specimen

Whole blood: Lavender EDTA, K2EDTA

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Lead: Clotted samples
ZPP: Hemolyzed & clotted samples

Stability

ZPP:
Room temperature: 8 days
Refrigerated: 60 days
Frozen: Unacceptable

Lead:
Room temperature: 7 days
Refrigerated: 30 days
Frozen: Not recommended

Methodology

Atomic Absorption Spectrophotometry/Fluorometry
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Reference Range

COMPONENTS REFERENCE INTERVAL
Lead, Whole Blood <6 years: <3.5 µg/dL
Lead, Whole Blood >=6 years: <5.0 µg/dL

Zinc Protoporphyrin (ZPP), Whole Blood:
0-69 µmol/mol heme

Zinc Protoporphyrin (ZPP),
Whole Blood: 0-40 µg/dL

These results should be interpreted in the context of
OSHA, CDC, and local and state occupational
health requirements. Additional information is
available through the following
link:
https://www.cdc.gov/niosh/topics/ables/description.html

For occupational exposure to lead, OSHA requires ZPP
whole blood concentration to be reported in units of
ug/dL. For adults, conversion of ZPP to units of ug/dL
assumes a hemoglobin level of 15 g/dL.
Methodology used in lead analysis is atomic absorption.
Methodology used for ZPP is Protofluor Z system manufactured
by Helena Laboratories. This test has been modified from the
manufacturer's instructions.
Elevated results may be due to skin or collection-related
contamination, including the use of a noncertified
lead-free tube,or transfer of sample into a noncertified
lead-free tube. If contamination concerns exist due to
elevated levels of blood lead, confirmation with a venous
specimen collected in a certified lead-free tube is
recommended.
The Blood Lead test was developed and the performance
characteristics determined by Warde Medical Laboratory.
It has not been cleared or approved by the FDA.
The laboratory is regulated under CLIA as qualified to
perform high-complexity testing. This test is used for
patient testing purposes. It should not be regarded
as investigational or for research.
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Performing Laboratory

Warde Medical Laboratory
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DUE TO A NATIONWIDE SHORTAGE OF DARK BLUE EDTA TRACE ELEMENT TUBES, WARDE LAB IS TEMPORARILY ACCEPTING LAVENDER EDTA TUBES.