Test Details
Mnemonic
ZPPI
Ordering Code
1001560
CPT-4 Code(s)
83655 (Lead), 84202 (Zinc Protoporphyrin)
Specimen Information
Collect
Dark blue trace element EDTA
Specimen Preparation
Send 7.0 mL whole blood refrigerated. PROTECT FROM LIGHT.
A completed lead requisition must accompany sample.
A completed lead requisition must accompany sample.
Alternate Specimen
Whole blood: Lavender EDTA, K2EDTA
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated
Rejection Criteria
Lead: Clotted samples
ZPP: Hemolyzed & clotted samples
ZPP: Hemolyzed & clotted samples
Stability
ZPP:
Room temperature: 8 days
Refrigerated: 60 days
Frozen: Unacceptable
Lead:
Room temperature: 7 days
Refrigerated: 30 days
Frozen: Not recommended
Room temperature: 8 days
Refrigerated: 60 days
Frozen: Unacceptable
Lead:
Room temperature: 7 days
Refrigerated: 30 days
Frozen: Not recommended
Methodology
Atomic Absorption Spectrophotometry/Fluorometry
Reference Range
COMPONENTS REFERENCE INTERVAL
Lead, Whole Blood <6 years: <3.5 µg/dL
Lead, Whole Blood >=6 years: <5.0 µg/dL
Zinc Protoporphyrin (ZPP), Whole Blood:
0-69 µmol/mol heme
Zinc Protoporphyrin (ZPP),
Whole Blood: 0-40 µg/dL
These results should be interpreted in the context of
OSHA, CDC, and local and state occupational
health requirements. Additional information is
available through the following
link:
https://www.cdc.gov/niosh/topics/ables/description.html
For occupational exposure to lead, OSHA requires ZPP
whole blood concentration to be reported in units of
ug/dL. For adults, conversion of ZPP to units of ug/dL
assumes a hemoglobin level of 15 g/dL.
Methodology used in lead analysis is atomic absorption.
Methodology used for ZPP is Protofluor Z system manufactured
by Helena Laboratories. This test has been modified from the
manufacturer's instructions.
Elevated results may be due to skin or collection-related
contamination, including the use of a noncertified
lead-free tube,or transfer of sample into a noncertified
lead-free tube. If contamination concerns exist due to
elevated levels of blood lead, confirmation with a venous
specimen collected in a certified lead-free tube is
recommended.
The Blood Lead test was developed and the performance
characteristics determined by Warde Medical Laboratory.
It has not been cleared or approved by the FDA.
The laboratory is regulated under CLIA as qualified to
perform high-complexity testing. This test is used for
patient testing purposes. It should not be regarded
as investigational or for research.
Lead, Whole Blood <6 years: <3.5 µg/dL
Lead, Whole Blood >=6 years: <5.0 µg/dL
Zinc Protoporphyrin (ZPP), Whole Blood:
0-69 µmol/mol heme
Zinc Protoporphyrin (ZPP),
Whole Blood: 0-40 µg/dL
These results should be interpreted in the context of
OSHA, CDC, and local and state occupational
health requirements. Additional information is
available through the following
link:
https://www.cdc.gov/niosh/topics/ables/description.html
For occupational exposure to lead, OSHA requires ZPP
whole blood concentration to be reported in units of
ug/dL. For adults, conversion of ZPP to units of ug/dL
assumes a hemoglobin level of 15 g/dL.
Methodology used in lead analysis is atomic absorption.
Methodology used for ZPP is Protofluor Z system manufactured
by Helena Laboratories. This test has been modified from the
manufacturer's instructions.
Elevated results may be due to skin or collection-related
contamination, including the use of a noncertified
lead-free tube,or transfer of sample into a noncertified
lead-free tube. If contamination concerns exist due to
elevated levels of blood lead, confirmation with a venous
specimen collected in a certified lead-free tube is
recommended.
The Blood Lead test was developed and the performance
characteristics determined by Warde Medical Laboratory.
It has not been cleared or approved by the FDA.
The laboratory is regulated under CLIA as qualified to
perform high-complexity testing. This test is used for
patient testing purposes. It should not be regarded
as investigational or for research.
Performing Laboratory
Warde Medical Laboratory
New York DOH Approval Status
Yes