Test Details
Mnemonic
UMETR
Ordering Code
1013300
CPT-4 Code(s)
83835, 82570
Specimen Information
Patient Preparation
Medications that may interfere with metanephrine include amphetamines and amphetamine - like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, carbidopa - levopa (Sinemet), clonidine, dexamethasone, diuretics (in doses sufficient to deplete sodium), methyldopa (aldomet), MOA inhibitors, nose drops, propafenone (Rythmol), tricyclic antidepressants, and vasodilators. Patient should consult their physician before discontinuing any medication.
Collect
Random urine
Specimen Preparation
Add 1 - 2 drops 6N HCl to a 10 mL urine within 4 hours on collection. Mix well, ensure pH is between 1 - 3, and send 10.0 mL urine in a screw capped plastic urine cup.
Alternate Specimen
Collect random urine, mix well and send 10.0 mL urine in a screw capped plastic urine container.
Minimum Volume
5.0 mL
Transport Temperature
Refrigerated
Rejection Criteria
Samples with pH <1
Stability
With preservative:
Room temperature: 9 days
Refrigerated: 9 days
Frozen: 30 days
Room temperature: 9 days
Refrigerated: 9 days
Frozen: 30 days
Methodology
High Performance Liquid Chromatography
Reference Range
Metanephrine 3 - 20 µg/g creatinine
Normetanephrine 10 - 45 µg/g creatinine
Normetanephrine 10 - 45 µg/g creatinine
Performing Laboratory
Warde Medical Laboratory
New York DOH Approval Status
Yes