Test Details
Mnemonic
TMSI
Ordering Code
3800241
CPT-4 Code(s)
81301, 88381
Specimen Information
Patient Preparation
Pathology report must accompany specimen in order for testing to be performed. This assay requires at least 40% tumor nuclei for endometrial specimens and at least 20% tumor nuclei for colorectal specimens.
Collect
Tissue block
Specimen Preparation
Send a formalin-fixed paraffin embedded tissue block, (non-decalcified), with approximately 72 mm(2) area of tumor.
Alternate Specimen
Tissue slide: 1 Slide stained with hematoxylin and eosin and 10 Unstained, nonbaked slides with
5-micron thick sections of the tumor tissue.
Note: The total amount of required tumor nuclei can be obtained by scraping up to 10 slides
from the same block. Unused unstained slides will not be returned.
5-micron thick sections of the tumor tissue.
Note: The total amount of required tumor nuclei can be obtained by scraping up to 10 slides
from the same block. Unused unstained slides will not be returned.
Minimum Volume
18 mm(2) area of tumor
Transport Temperature
Room temperature
Rejection Criteria
Decalcified specimens, Low tumor percentage, insufficient amount of tumor nonformalin fixed, fresh tissue Cytology smears
Stability
Room temperature: Indefinitely
Refrigerated: Unacceptable
Frozen: Unacceptable
Refrigerated: Unacceptable
Frozen: Unacceptable
Methodology
Polymerase Chain Reaction (PCR)
Reference Range
See report
Performing Laboratory
MAYO
New York DOH Approval Status
Yes