Test Details
Mnemonic
MLH1
Ordering Code
3624180
CPT-4 Code(s)
81288
Specimen Information
Collect
Tumor tissue
Specimen Preparation
Send formalin fixed paraffin embedded tissue block or 5 unstained 5 micron slides in a tissue transport kit. Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of
the following: an order comment indicating that the ARUP pathologist should choose the
specimen most appropriate for testing, or individual orders for each sample submitted. A
Pathologist Block Selection Fee will be added to orders that utilize the first option. If multiple
specimens are sent to ARUP without a request for pathologist block/slide selection or individual
orders, they will be held until clarification is provided.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of
the following: an order comment indicating that the ARUP pathologist should choose the
specimen most appropriate for testing, or individual orders for each sample submitted. A
Pathologist Block Selection Fee will be added to orders that utilize the first option. If multiple
specimens are sent to ARUP without a request for pathologist block/slide selection or individual
orders, they will be held until clarification is provided.
Minimum Volume
5 slides (if using)
Transport Temperature
Room temperature
Rejection Criteria
Fixative other than 10 percent neutral buffered formalin, decalcified specimens (except in
EDTA), less than 20 percent tumor.
EDTA), less than 20 percent tumor.
Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable
Refrigerated: Indefinite
Frozen: Unacceptable
Methodology
Real-Time Polymerase Chain Reaction/Fluorescence Resonance Energy Transfer
Reference Range
See report
Performing Laboratory
ARUP
New York DOH Approval Status
Yes