Test Details

Mnemonic

MPA01

Ordering Code

1757260

CPT-4 Code(s)

80180

Specimen Information

Patient Preparation

Collect specimen 12 hours post-dose.

Collect

Red top

Specimen Preparation

Centrifuge and separate serum from cells within 2 hours. Send 1.0 mL serum in screw capped plastic vial.

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Serum separator tube (SST), grossly lipemic, hemolyzed, and icteric specimens.

Stability

Room temperature: Unacceptable
Refrigerated: 4 days
Frozen: 1 month

Methodology

High Performance Liquid Chromatography/Tandem Mass Spectrometry
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Reference Range

Mycophenolic Acid: 1.0 - 3.5 ug/mL
Toxic level for MPA: >25 mg/mL
Toxic level for MPA-glucuronide: Not established
Combined therapy with cyclosporin: 1.0 - 35 mcg/mL
Combined therapy with TQC volumes: 1.9 - 4.0 mcg/mL
Mycophenolic Acid Glucuronide: 35.0 - 100.0 ug/mL
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Performing Laboratory

Warde Medical Laboratory
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New York DOH Approval Status

No
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