Test Details
Mnemonic
MPA01
Ordering Code
1757260
CPT-4 Code(s)
80180
Specimen Information
Patient Preparation
Collect specimen 12 hours post-dose.
Collect
Red top
Specimen Preparation
Centrifuge and separate serum from cells within 2 hours. Send 1.0 mL serum in screw capped plastic vial.
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated
Rejection Criteria
Serum separator tube (SST), grossly lipemic, hemolyzed, and icteric specimens.
Stability
Room temperature: Unacceptable
Refrigerated: 4 days
Frozen: 1 month
Refrigerated: 4 days
Frozen: 1 month
Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry
Reference Range
Mycophenolic Acid: 1.0 - 3.5 ug/mL
Toxic level for MPA: >25 mg/mL
Toxic level for MPA-glucuronide: Not established
Combined therapy with cyclosporin: 1.0 - 35 mcg/mL
Combined therapy with TQC volumes: 1.9 - 4.0 mcg/mL
Mycophenolic Acid Glucuronide: 35.0 - 100.0 ug/mL
Toxic level for MPA: >25 mg/mL
Toxic level for MPA-glucuronide: Not established
Combined therapy with cyclosporin: 1.0 - 35 mcg/mL
Combined therapy with TQC volumes: 1.9 - 4.0 mcg/mL
Mycophenolic Acid Glucuronide: 35.0 - 100.0 ug/mL
Performing Laboratory
Warde Medical Laboratory
New York DOH Approval Status
No