Test Details

Mnemonic

SERT

Ordering Code

3685700

CPT-4 Code(s)

80332 (G0480)

Specimen Information

Patient Preparation

Pre-dose draw at steady state concentration.

Collect

Red top

Specimen Preparation

Centrifuge, separate serum from cells within 2 hours of collection and send 1.0 mL serum in a screw capped plastic vial.

Alternate Specimen

Plasma: Lavender EDTA

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated

Rejection Criteria

Serum separator tube (SST) or PST (Polymer gel separation tube), whole blood, citrated plasma or ACD plasma

Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 6 months

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry
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Reference Range

Toxic: >300 ng/mL
Sertraline doses ranging from 50 - 200 mg/d produce serum concentration ranging from 30 - 200 ng/mL. Dosing above 200 mg/d is associated with increased adverse effects and decreased efficacy. Adverse effects may include dry mouth, headache, dizziness, somnolence, nausea and diarrhea.
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Performing Laboratory

ARUP Reference Laboratory
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New York DOH Approval Status

Yes
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