Test Details
Mnemonic
VEDOZ
Ordering Code
3800094
CPT-4 Code(s)
80280
Specimen Information
Patient Preparation
12 hours prior to testing: Do not take multivitamins or dietary supplements containing biotin (Vitamin B7).
Nivolumab must be discontinued at least 4 weeks prior to testing.
Nivolumab must be discontinued at least 4 weeks prior to testing.
Collect
Red top
Specimen Preparation
Centrifuge within 2 hours of collection and send 1.5 mL refrigerated in a screw capped plastic vial.
Alternate Specimen
Serum separator tube (SST)
Minimum Volume
0.75 mL
Transport Temperature
Refrigerated
Rejection Criteria
Gross hemolysis, lipemia or icterus samples
Stability
Room temperature: Unacceptable
Refrigerated: 28 days
Frozen: 28 days
Refrigerated: 28 days
Frozen: 28 days
Methodology
Vedolizumab Quant: Liquid Chromatography - Mass Spectrometry (LC-MS/MS)
Vedolizumab Antibodies: Electrochemiluminescent Bridging Immunoassay
Vedolizumab Antibodies: Electrochemiluminescent Bridging Immunoassay
Reference Range
VEDOLIZUMAB QUANTITATION:
Vedolizumab lower limit of quantitation = 2.0 mcg/mL
VEDOLIZUMAB ANTIBODIES:
Antibodies to vedolizumab: <9.8 ng/mL
Vedolizumab lower limit of quantitation = 2.0 mcg/mL
VEDOLIZUMAB ANTIBODIES:
Antibodies to vedolizumab: <9.8 ng/mL
Performing Laboratory
Mayo Clinic Laboratories
New York DOH Approval Status
Yes