Test Details

Mnemonic

VEDOZ

Ordering Code

3800094

CPT-4 Code(s)

80280

Specimen Information

Patient Preparation

12 hours prior to testing: Do not take multivitamins or dietary supplements containing biotin (Vitamin B7).

Nivolumab must be discontinued at least 4 weeks prior to testing.

Collect

Red top

Specimen Preparation

Centrifuge within 2 hours of collection and send 1.5 mL refrigerated in a screw capped plastic vial.

Alternate Specimen

Serum separator tube (SST)

Minimum Volume

0.75 mL

Transport Temperature

Refrigerated

Rejection Criteria

Gross hemolysis, lipemia or icterus samples

Stability

Room temperature: Unacceptable
Refrigerated: 28 days
Frozen: 28 days

Methodology

Vedolizumab Quant: Liquid Chromatography - Mass Spectrometry (LC-MS/MS)
Vedolizumab Antibodies: Electrochemiluminescent Bridging Immunoassay
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Reference Range

VEDOLIZUMAB QUANTITATION:
Vedolizumab lower limit of quantitation = 2.0 mcg/mL
VEDOLIZUMAB ANTIBODIES:
Antibodies to vedolizumab: <9.8 ng/mL
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Performing Laboratory

Mayo Clinic Laboratories
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